ELSI-Dedicated Genome Engineering Working Group
The Dark Matter Project is proud to launch EDGE: ELSI-Dedicated Genome Engineering Working Group, co-chaired by Ran Brosh and Carolyn Chapman.
EDGE’s mission is to make sure the broad ethical, legal, and social implications (ELSI) of scientific innovation in Big DNA technology are considered as it happens. For example, EDGE plans to delineate ELSI related to genomically-rewritten and tailored genetically engineered mouse models (GREAT GEMMS).
Publications
Read our latest Perspective:
Synthetic biology and genome engineering in support of human, agricultural, and environmental security.
Chapman et al., Front. Bioeng. Biotechnol. 2026.
Webinar Series: Rewriting Life—The Science, Ethics and Regulation of Mammalian Genome Engineering
Introductory Webinar: The Science, Ethics and Regulation of Mammalian Genome Engineering.
Featuring Drs. Jef Boeke and Carolyn Chapman.
Genetic modification of pigs for xenotransplantation: Towards a solution for the organ shortage crisis.
Dr. David Ayares.
Genetic modification of pigs for xenotransplantation: Ethics and Regulation
Dr. Heather Lombardi and Mr. Brendan Parent.
NYU Langone Division of Medical Ethics — Synthetic Biology Ethics Lesson Plan
Written by Claire Lin
Supervised by Dr. Carolyn Chapman
With support from Ms. Lisa Kearns, MS MA, Associate Director of the NYU’s Division of Medical Ethics High School Bioethics Project
